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Researchers have found a novel form of the Alzheimer's protein tau in the fluid surrounding the brain and spinal cord. This form of tau -- known as MTBR tau -- indicates what stage of Alzheimer's a person is in and…
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A new study on Alzheimer's disease has revealed a previously unknown biochemical cascade in the brain that leads to the destruction of synapses, the connections between nerve cells that are responsible for memory and cognition.
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Researchers have found new forms of tau protein that become abnormal in the very early stages of Alzheimer's disease before cognitive problems develop. The scientists developed new tools to detect these subtle changes and confirmed their results in human samples.
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A team of researchers has taken a major step toward understanding the mechanisms involved in the formation of large clumps of tau protein, a hallmark of Alzheimer's disease and several other neurodegenerative disorders.
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A new study found that Medicare beneficiaries who go on to be diagnosed with dementia are more likely to miss payments on bills as early as six years before a clinical diagnosis.
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A new study has found that among older Americans with cognitive impairment, the greater the air pollution in their neighborhood, the higher the likelihood of amyloid plaques - a hallmark of Alzheimer's disease. The study adds to a body of…
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A proof-of-concept study conducted in a mouse model of Alzheimer's disease offers new evidence that copper isotopes can be used to detect the amyloid-beta protein deposits that form in the brains of people living with -- or at risk of…
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Anxiety is associated with an increased rate of progression from mild cognitive impairment to Alzheimer's disease, according to a new study.
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A research team has discovered that Dlgap2, a gene that helps facilitate communication between neurons in the nervous system, is associated with the degree of memory loss in mice and risk for Alzheimer's dementia in humans. When studying post-mortem human…
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Researchers find a key mutation causing abnormal transport of BACE1, the enzyme responsible for processing the Alzheimer's disease-linked amyloid protein. Identification of this mutation, which is more common among African Americans with Alzheimer's, may allow early intervention.
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New research explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease (AD).
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A study has identified certain regions in the retina - the lining found in the back of the eye - that are more affected by Alzheimer's disease than other areas. The findings may help physicians predict changes in the brain…
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Alzheimer's disease develops over decades. It begins with a fatal chain reaction in which masses of misfolded beta-amyloid proteins are produced that in the end literally flood the brain. Researchers now show that this chain reaction starts much earlier in…
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Researchers have demonstrated that the severity of 'reactive astrocytes' is a key indicator for the onset of Alzheimer's disease.
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In recent years, the scientific community has suspected that the gut microbiota plays a role in the development of the disease. A team now confirms the correlation, in humans, between an imbalance in the gut microbiota and the development of…
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Exercising more than once per week is associated with a lower risk of developing Alzheimer's disease in patients with mild cognitive impairment.
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Both of Andrew Kiselica's grandfathers developed dementia when he was in graduate school.
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A new study by Monash University has found that obstructive sleep apnea (OSA) has been linked to an increased risk of dementia.
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A team has identified several new potential molecular targets in endothelial cells and microglia for AD drug development.
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In Alzheimer's disease, a protein (peptide) forms clumps in the brain and causes sufferers to lose their memory. A research group has now described a new treatment method that increases the body's own degradation of the building blocks that lead…
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