Sylvie Belleville, MD, PhD from the University of Montréal, Montréal, Canada talks to us about an upcoming study which will set out to examine whether a combination of formal brain training and leisure activities can increase the reserve processes in patients at risk of dementia development. Prof. Belleville explains how the cohort will be enriched, and how this will help answer the study’s objective. This interview was recorded at the 2017 Alzheimer’s Association International Conference (AAIC) held in London, UK.