Kirsty McAleese, PhD, of Newcastle University, Newcastle, UK, discusses her research into fibrinogen leakage in the white matter of Alzheimer’s disease and normal aged brains, and the implications of the findings for fibrinogen as a biomarker. Dr McAleese highlights the notable results for extravascular fibrinogen and cerebral small vessel disease pathology. This interview took place at the Alzheimer’s Research UK (ARUK) Conference 2019, held in Harrogate, UK.