Lars Wojtecki, MD, PhD, Institute of Clinical Neuroscience and Medical Psychology, University Düsseldorf, Düsseldorf, Germany, discusses the short and long-term clinical results of transcranial pulse stimulation (TPS) in Alzheimer’s disease. After one year, results show stable effects on cognitive measures after TPS. Still, the effect is not yet significant; this may be because the study was underpowered since only a small group of patients were available for long-term follow-up. The following steps of this investigation will be to finalize the long-term follow-up with the entire group of patients. Additionally, the results from the Austrian prospective, placebo-controlled clinical trial are highly anticipated as they will provide a better understanding of the effect of TPS on Alzheimer’s disease. This interview took place at the European Academy of Neurology (EAN) 2022 Congress in Vienna, Austria.