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ARUK 2021 | CNS involvement by SARS-CoV-2: what do we know?

SARS-CoV-2 is a new type of coronavirus that causes the Coronavirus Disease 2019 (COVID-19), which has been the most challenging pandemic in this century. Clayton Wiley, MD, PhD, University of Pittsburgh, Pittsburgh, PA, shares what is currently known about central nervous system (CNS) involvement by SARS-CoV-2 and whether or not SARS-CoV-2 is capable of infecting/affecting the human CNS. At this time, there is no evidence that SARS-CoV-2 infects the brain. However, the virus does not need to infect the brain to affect it. SARS-CoV-2 seems to affect the brain by causing coagulation disorders. Prof. Wiley highlights that this virus can act as a stressor and cause secondary degeneration. This interview took place during the Alzheimer’s Research UK (ARUK) Conference 2021.