Atticus Hainsworth, PhD, St. George’s University of London, describes his highlights from the Alzheimer’s Association International Conference (AAIC), 2021. Dr Hainsworth states that the range of approaches taken by researchers examining the contribution of vascular disease to dementia is impressive. Alongside discussing aducanumab, a monoclonal antibody now licensed for Alzheimer’s disease, he also spotlights talks on repurposing existing drugs and the role of immune cells in stroke. He concludes by sharing his thoughts on the SPRINT-MIND study, investigating the effectiveness of an intensive blood pressure-lowering regimen on reducing cognitive impairment. This interview took place during the Alzheimer’s Association International Conference (AAIC), 2021.