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AAIC 2020 | Representative population for Alzheimer’s disease research

Suzanne Schindler, MD, PhD, Washington University in St. Louis School of Medicine, St. Louis, MO, discusses the importance of a representative research population for the p-tau isoform and amyloid-β 42/40 ratio biomarkers. Usually, the research population is largely homogeneous (non-Hispanic, highly-educated white individuals with lower medical comorbidity), not necessarily representative of a clinical population. Therefore, the biomarker blood test must be studied on a more diverse, broader socioeconomic groups. This interview was recorded during an online conference call with The Video Journal of Dementia (VJDementia).