The role of selective mitophagy in the pathogenesis of neurodegenerative diseases

Mitophagy is a highly important process involved in preserving a healthy network of working neurons, but can this mechanism be modulated to selectively target other pathways that play a role in the progression of different neurodegenerative diseases? Here, Helene Plun-Favreau, PhD, from University College London, London, UK, gives an overview of mitophagy and how this process can act as a therapeutic target in most, if not all, neurodegenerative diseases. This interview was recorded at the Alzheimer’s Research UK (ARUK) Conference 2018, held in London, UK.

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