Understanding the molecular mechanisms underlying dementia is fundamental to developing treatments. In this interview, Diane Hanger, PhD, of King’s College London, London, UK, discusses the areas she was particularly excited to hear about at the Alzheimer’s Research UK (ARUK) Conference 2018, held in London, UK. Some of the exciting fields Prof. Hanger highlights include synaptic biology, non-neuronal cell involvement, presenilin and, of course, tau.